The 49-year-old actress opened up about the life-changing diagnosis in a series of tweets.

Actress Christina Applegate has been diagnosed with multiple sclerosis.

“It’s been a strange journey.

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“It’s been a tough road.

But as we all know, the road keeps up going.

Unless some ahole blocks it.”

And that’s what I do.

So now I ask for privacy.

As I go through this thing.

Thank you xo.”

Some symptoms can include blurred vision, slurred speech, and difficulty with coordination, among others.

Applegate has long been open about her health journey over the years.

Since opening up about her multiple sclerosis diagnosis, Applegate has received a flurry of well-wishes from fans online.

“One of my family members has MS. Hugs to you.

You’ve shown us you are strong before.

And there is a whole community supporting you.

If anyone has exemplified resilience over the years, it’s Applegate.